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Buy Tolperisone online. PayPal

 

Pharmacological group: Muscle relaxant (Myorelaxant).

 

Dosage form: tablets (50 mg), tablets (150 mg), ampules (0,0025 ml) .

 

Release form: One package of Tolperisone consists of 30 tables.

One package of Tolperisone for injections consists of 5 ampules.

 

Tolperisone is a centrally acting muscle relaxant, H-anticholinergic. Reduces muscle tone and is used for the symptomatic treatment of muscle spasms and other diseases accompanied by increased tone or dystonia.

 

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Buy Tolperisone

HintaAlkaen 30,00$
  • The mechanism of action is not fully understood. Tolperisone has a high affinity for nervous tissue, reaching the highest concentrations in the brain stem, spinal cord and peripheral nervous system. The main effect of tolperisone is mediated by inhibition of the spinal reflex arcs. Probably, this effect, together with the elimination of the facilitation of the conduction of excitation along the descending pathways, provides the therapeutic effect of tolperisone. The chemical structure of tolperisone is similar to that of lidocaine. Like lidocaine, it has a membrane-stabilizing effect and reduces the electrical excitability of motor neurons and primary afferent fibers. Tolperisone dose-dependently inhibits the activity of voltage-gated sodium channels. Accordingly, the amplitude and frequency of the action potential decreases. An inhibitory effect on voltage-gated calcium channels has been proven. It is assumed that, in addition to its membrane-stabilizing action, tolperisone may also inhibit the release of the mediator. Tolperisone has some weak properties of α-adrenergic antagonists and antimuscarinic action.

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