Buy Zyrtec

The drug is prescribed inside.

Adults and children over 6 years of age are prescribed in a dose of 10 mg (1 table or 20 drops) / day. Adults-10 mg once a day; children - 5 mg 2 times / day or 10 mg 1 time / day. Sometimes an initial dose of 5 mg may be sufficient to achieve a therapeutic effect.

Children aged 2 to 6 years are prescribed 2.5 mg (5 drops) 2 times / day or 5 mg (10 drops) 1 time / day.

Children aged 1 to 2 years are prescribed 2.5 mg (5 drops) up to 2 times / day.

Children aged 6 months to 12 months are prescribed 2.5 mg (5 drops) 1 time / day.

With renal failure and in elderly patients, the dose of the drug should be adjusted depending on the magnitude of the CC.

QA can be calculated from the serum creatinine concentration using the following formula:

For men: CK (ml / min) = [140 - age (years)] x body weight (kg) / 72 x serum creatinine (mg / dL);

KK for women can be calculated by multiplying the obtained value by a factor of 0.85.

Adults with renal and hepatic impairment dose set according to the following table.

Renal insufficiency KK (ml / min) Dosing regimen:
Norm 80 10 mg / day;
Light 50-79 10 mg / day;
Average 30-49 5 mg / day;
Severe <30 5 mg every other day.
Terminal stage - patients on dialysis <10 The drug is contraindicated
Patients with a violation of only liver function correction of the dosing regimen is not required.

In the study of the drug interaction of cetirizine with pseudoephedrine, cimetidine, ketoconazole, erythromycin, azithromycin, glipizide and diazepam, no clinically significant undesirable interaction was detected.

With a simultaneous appointment with theophylline (400 mg / day), the total clearance of cetirizine is reduced by 16% (theophylline kinetics does not change).

With simultaneous administration with macrolides and ketoconazole, there were no changes on the ECG.

When using the drug in therapeutic doses of data on the interaction with alcohol (at a blood alcohol concentration of 0.5 g / l) is not obtained. Nevertheless, the patient should refrain from drinking alcohol during therapy with the drug in order to avoid oppression of the CNS.