Buy Baclofen (Baclosan)

• Spasticity in multiple sclerosis,
• strokes,
• craniocerebral trauma,
• meningitis,
• spinal diseases (infectious, degenerative, tumor and traumatic genesis),
• in infantile cerebral palsy.

Alcoholism

In France, since March 2014, the medical authorities (ANSM: Agence nationale de sécurité des medicaments et des produits de santé) have authorized the prescription of baclofen for the treatment of drug addiction. clinical tests conducted on patients with alcoholism (from 2008 to 2014) showed very good positive results. Regardless of the level of alcohol consumption and the duration of consumption (chronic patients or casual users who drink excessive doses), the results of baclofen treatment have been amazing. Almost 80%  of patients got rid of alcohol dependence. This property of baclofen was noticed in France by Olivier Ameisen, M.D., a cardiologist turned alcoholic and treated with the drug. Public opinion was not ready for such an unusually easy cure for alcoholism, since traditional and far from cheap methods of treatment through therapy in rehabilitation centers do not lead to such remarkable results. Dr. Olivier Ameisen, faced with medical skepticism about the use of a neurological drug to treat alcohol addiction. Therefore, he wrote the book "The Last Glass" (Dernier verre, Dr. Oliver Ameisen, Denoel, 2008), in which he recounted his case in detail and thereby mobilized public opinion.  Following this book, several clinical trials were organized in France under the supervision of government agencies. The above results of these tests led the French medical authorities to approve the use of baclofen in the treatment of alcohol dependence. To date, the parameters regarding dosage and side effects are not entirely clear. The dosage depends on the degree of dependence and on the physiology of each patient.

• Hypersensitivity,
• epilepsy,
• convulsions (history),
• psychosis,
• Parkinson's disease,
• chronic renal failure.

Use with caution with:

• cerebrovascular insufficiency,
• atherosclerosis of the cerebral vessels,
• peptic ulcer of the stomach and duodenal ulcer,
• pregnancy,
• lactation,
• old age,
• children (up to 12 years)

Inside, during meals: the initial dose is 5 mg 3 times a day, followed by an increase in the dose every 3 days by 5 mg until the effect is achieved, usually no more than 20-25 mg 3 times a day; the maximum dose is 100 mg / day (for a short time in a hospital setting). The final dose is set so that the decrease in muscle tone does not lead to excessive myasthenia gravis and does not impair motor function. With increased sensitivity, the initial daily dose is 5-10 mg, followed by a slower increase. In chronic renal failure and during hemodialysis - a daily dose of 5 mg. In children under 10 years of age, the daily dose is 0.75-2 mg / kg, over 10 years old - 2.5 mg / kg; initial dose - 1.5-2 mg / kg 4 times a day, maintenance dose for children 1-2 years old - 10-20 mg / day, 2-10 years old - 30-60 mg / day. Cancellation of the drug is carried out gradually (within 1-2 weeks). If the initial doses are not observed, as well as the independent increase in the dosage, the drug can cause drug dependence.

• Nausea,
• vomiting,
• drowsiness,
• dizziness,
• asthenia,
• dry mouth,
• confusion,
• gait disturbance,
• urinary retention,
• constipation or diarrhea,
• decreased blood pressure,
• apathy;
• euphoria,
• depression,
• paresthesia,
• myalgia,
• myasthenia gravis,
• ataxia,
• tremor,
• nystagmus,
• accommodation paresis,
• hallucinations,
• dysuria,
• enuresis;
• convulsions,
• a decrease in the convulsive threshold,
• mydriasis,
• an increase in body weight.

With prolonged use - impaired liver function.

Withdrawal syndrome

With a sharp withdrawal of the drug after a course of use lasting more than 2 months, hypermetabolism with hyperpyrexia, mental disorders, muscle stiffness, repeated manifestations of spasticity, which can develop into rhabdomyolysis, and internal organ failure can also occur. Resuming the drug at the same dosage as the drug before discontinuation reduces symptoms.

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Side effects are often transient in nature, they should be distinguished from the symptoms of the disease for which treatment is being carried out: with concomitant epilepsy, treatment is carried out without canceling antiepileptic drugs. In patients with liver diseases and diabetes mellitus, it is necessary to periodically monitor the activity of "hepatic" transaminases, alkaline phosphatase, blood glucose. During treatment, one should refrain from potentially dangerous activities associated with the need for increased attention and rapid mental and motor reactions.

The drug should be used in compliance with the initial doses in order to avoid drug dependence and withdrawal syndrome.