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Buy Quetiapine online. PayPal

 

Pharmacological group: atypical antipsychotic.

 

Active ingredient: Quetiapine.

 

Other brand names: Seroquel, Quetiapin Accord.

 

Dosage form: tablets

 

Release form: 60 tablets of 25, 100, 200, 300 or 400 mg per pack.

 

Quetiapine is used to treat chronic and acute schizophrenia, bipolar affective disorder, major depressive disorder (in combination with antidepressants), and certain other mental illnesses. Quetiapine is no less effective than typical antipsychotics in the treatment of productive symptoms, while it causes far fewer side effects. Its antipsychotic activity is comparable to that of haloperidol..

 

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Buy Quetiapine

PriceFrom $30.00
  • Quetiapine is an atypical antipsychotic drug. Quetiapine and its active metabolite N-desalkyl quetiapine interact with neurotransmitter receptors in the brain. Quetiapine and N-desalkyl quetiapine show high affinity for 5HT2 serotonin receptors and D1 and D2 dopamine receptors in the brain. Higher selectivity for serotonin receptors of the 5HT2 type than for dopamine D2 receptors determines the main clinical antipsychotic properties of Quetiapine-S3 and the low incidence of extrapyramidal side effects. In addition, N-desalkyl quetiapine exhibits a high affinity for the norepinephrine transporter. Quetiapine and N-desalkyl quetiapine have high affinity for histamine and α1-adrenergic receptors and less affinity for α2-adrenergic receptors and 5HT1 serotonin receptors. Quetiapine does not show significant affinity for cholinergic muscarinic and benzodiazepine receptors. In standard tests, quetiapine exhibits antipsychotic activity. The specific contribution of the N-desalkyl metabolite of quetiapine to the pharmacological activity of quetiapine has not been established. The results of the study of extrapyramidal symptoms (EPS) in animals revealed that quetiapine causes mild catalepsy at doses that effectively block D2 receptors. Quetiapine causes a selective decrease in the activity of mesolimbic A10 dopaminergic neurons in comparison with A9 nigrostriatal neurons involved in motor function.

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